Cannabidiol is a safe, non-intoxicating, and non-addictive cannabis compound with significant therapeutic attributes, but CBD-drug interactions may be problematic in some cases.
Research has shown that certain compounds in grapefruit can interact with many common pharmaceutical drugs by inhibiting cytochrome P450 enzymes, a family of liver enzymes that metabolizes these drugs. However, CBD can also inhibit these enzymes when consumed at high enough dosages.
We always recommend checking with your physician before starting a new dietary supplement program. Any instructions you may have received from a medical professional regarding grapefruit should be treated with the same level of care when it comes to CBD products.
To learn more about cytochrome P450 enzymes and CBD at Project CBD.